Molecular Biomarkers & Diagnosis

Joanna Zytynska- Daniluk

Publications

• Research Article
  Changes in Physiology and Pathophysiology of Calprotectin Excretion from Neonate to Adult
  Author(s): Barbara Lisowska- Myjak and Joanna Zytynska- DanilukBarbara Lisowska- Myjak and Joanna Zytynska- Daniluk
  
  Background: Measurement of faecal calprotectin (FCP) concentrations is a theoretically justified laboratory test used in lieu of quantitative evaluation of neutrophils penetrating into the intestinal lumen. This parameter is organspecific and identifies intestinal inflammation. Aim: Search for individual interpretation of the cut-off values for the FCP test, taking into consideration different age groups of patients and causes of intestinal inflammation. Methods: Review of the literature data about the calprotectin concentrations in the meconium and faeces of neonates, infants, older children and adults. Results: FCP levels in meconium and faeces of infants are significantly higher than the concentration in older children and adults. In adults FCP is a simple and sensitive screening test .. Read More»
  DOI: 10.4172/2155-9929.1000234

  Abstract PDF