Journal of Oncology Translational Research

John M Watkins

Publications

• Research Article
  Once Daily High-dose Radiation (≥60 Gy) Treatment in Limited Stage Small Cell Lung Cancer
  Author(s): Amir Zahra DO, Tangel Chang DO, Taher Abu Hejleh, Muhammad Furqan, Gerald H Clamon, Sudershan K Bhatia, John M Watkins, Sarah L Mott MS, Douglas R Spitz, John M Buatti and Bryan G AllenAmir Zahra DO, Tangel Chang DO, Taher Abu Hejleh, Muhammad Furqan, Gerald H Clamon, Sudershan K Bhatia, John M Watkins, Sarah L Mott MS, Douglas R Spitz, John M Buatti and Bryan G Allen
  
  Objective: To investigate outcomes and prognostic factors in patients treated with once daily high-dose (≥ 60 Gy) radiation therapy (HDRT) and concurrent platinum-based chemotherapy in limited stage small cell lung cancer (LSSCLC). While we await current phase III trials to determine optimal radiation dose fractionation schemes in LS-SCLC, we report our experience in LS-SCLC with once daily HDRT. We hypothesized that HDRT would achieve similar efficacy and tolerability as twice daily therapy. Methods: We conducted a single institution retrospective review of all patients with LS-SCLC who underwent curative intent treatment from 2005-2013. Patients treated with HDRT (≥ 60 Gy) and concurrent chemotherapy (cisplatin or carboplatin and etoposide) were included in our analysis. Clinico.. Read More»
  DOI: 10.4172/2476-2261.1000108

  Abstract PDF