Pulmonary & Respiratory Medicine

John Tsanakas

Publications

• Research Article
  Is Lung Clearance Index (LCI) Affected by the Severity of Lung Disease in CF?
  Author(s): Vasiliki Avramidou, Elpis Hatziagorou, Asterios Kampouras, Vasiliki Georgopoulou, Fotis Kirvasilis and John TsanakasVasiliki Avramidou, Elpis Hatziagorou, Asterios Kampouras, Vasiliki Georgopoulou, Fotis Kirvasilis and John Tsanakas
  
  Background: LCI has been proven an effective tool in the detection of lung disease in CF. Objectives: a) To assess the correlation of ventilation inhomogeneity indices with structural damages of the lung, among different groups of disease severity and b) To compare the associations among MBW parameters with spirometry and CT. Method: Forty-four children and adolescents with CF participated in the study. Spirometry and multiple breath washout tests were performed. All children had a HRCT scan. The study population was divided into two groups, according to FEV1% predicted values: Group A: ≥ 85% predicted (normal) and Group B: 40-84% predicted (mild-moderate disease). Results: The patients’ mean age was 12.9 (5.67; 23.25) years, mean FEV1: 91.22 ± 24.22% and mean LCI: 10.72 ± 3.. Read More»
  DOI: 10.4172/2161-105X.1000392

  Abstract PDF