Journal of Metabolic Syndrome

Jorge Suarez

Publications

• Review Article
  Metabolic Syndrome in Aging Heart: Molecular Insights
  Author(s): Julieta Díaz-Juárez, Gustavo Pastelín and Jorge SuarezJulieta Díaz-Juárez, Gustavo Pastelín and Jorge Suarez
  
  Risk factors that define the metabolic syndrome (MetS) develop with age increasing its prevalence. Therefore, MetS can be considered an age-related health problem. Mechanism involved in aging and MetS are incompletely understood. The goal of this review is to highlight novel molecular maladaptive mechanism that tiger cardiac disease and common in aging and MetS. We focus on mitochondrial energetic function as well as mitochondrial calcium handling. In addition, we analyzed the role of O-GlcNAcylation which is a posttranslational modification that triggers multiple signaling pathways... Read More»
  DOI: 10.4172/2167-0943.1000230

  Abstract PDF