Journal of Computer Science & Systems Biology

Julio Perez-Marquez

Publications

• Research Article
  SQRestriction: Bio-Informatics Software for Restriction Fragment Length Polymorphism of Batches of Sequences
  Author(s): Julio Perez-MarquezJulio Perez-Marquez
  
  Objective: The existing informatics applications are specialized in particular aspects of the enzymatic restriction analysis of nucleotides sequences. In order to design an application that fulfills different needs of the investigation in restriction enzyme analysis, I have developed SQRestriction (SQR), a suite that compiles several utilities. Methods: I applied object-oriented programming to set algorithms in C++ that compare the differences or similarities in the restriction sites of orthologous genes or in nucleotide sequences with single nucleotide polymorphisms, insertions or deletions. Results: SQR is mainly a tool for the analysis of restriction fragment length polymorphisms but it has also other applications such as cloning of DNA; I demonstrate those func.. Read More»
  DOI: 10.4172/jcsb.1000155

  Abstract PDF