Journal of Nephrology & Therapeutics

K Kalem

Publications

• Case Report
  Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome, Two New Cases and Review of the Literature
  Author(s): Aicha Laidoudi, D Hakem, A Ghout, A Boukrara, S Medaoud, A Boudjelida, M Salah, D Boulfani, F Haddoum, Djenane, K Kalem and A BerrahAicha Laidoudi, D Hakem, A Ghout, A Boukrara, S Medaoud, A Boudjelida, M Salah, D Boulfani, F Haddoum, Djenane, K Kalem and A Berrah
  
  Case 1: A 25 year-old woman, presented with asthenia; weight loss; severe hypertension and acute unilateral anterior uveitis. She had also proteinuria; hematuria; aciduria; kidney failure and grade I hypertensive retinopathy. Kidney biopsy showed a non caseating granuloma in the interstitial tissue, and tubulointerstitial nephritis (TIN) with granulomatous lesions in the medullary parenchyma. All explorations were negative but QuantiFERON was 10 times normal without koch’s bacillus. No other sites of granulomas. The patient partially responded to corticoid treatment. She replased after untimely stopping corticosteroids. Corticosteroid-sparing was provided by mycophenolate mofetil. Case 2: A 46 year-old patient, with family history of mother who died of CKD, presented with recurrent anterior uveitis, kidney failure, proteinuria, and inflammatory syndr.. Read More»
  DOI: 10.4172/2161-0959.1000252

  Abstract PDF