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Research Article
Expression of Polymerase I and Transcript Release Factor (PTRF) in Lung Adenocarcinoma
Author(s): Kabulo K Cedric, Abdelhakam G Tamomh, Mohammad Abdul Mazid and Tesfaye Z WeldegiorgisKabulo K Cedric, Abdelhakam G Tamomh, Mohammad Abdul Mazid and Tesfaye Z Weldegiorgis
Aim: In our study we found the Lung cancer is a most common malignant tumor and important cause of cancerrelated death worldwide. Lung Adenocarcinoma is the most ordinary type of lung cancer, accounting for about 20-30% of lung cancer. The aims of this study to investigate the expression of PTRF in lung adenocarcinoma and determine if the loss of PTRF expression occur with the progression of lung adenocarcinoma.
Material and Methods: Immunohistochemistry and western blot were used to verify the PTRF expression in lung adenocarcinoma (LADC) and normal lung (NL). And PTRF expression status was also detected in the lung adenocarcinoma cells by western blot.
Results: Totally 41 differentially expression proteins were identified. Eighte.. Read More»
Journal of Oncology Medicine & Practice received 142 citations as per Google Scholar report