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Chemical Sciences Journal

ISSN: 2150-3494

Open Access

Kah Hin Low


Malaysia

Publications
  • Research Article
    Use of SPME and Chemometrics in Method Development for Food and Environmental Analysis of Pesticide Residues
    Author(s): Guan Huat Tan, Kah Hin Low and Adijat AwoniranGuan Huat Tan, Kah Hin Low and Adijat Awoniran

    The need to analyze multi pesticide residues continues to be imperative and applying a suitable experimental design remains the core to achieving a comprehensive chemical analysis. The pretreatment of a sample has been found to be the most important rate-determining step as it affects the instrumental process and data analysis. The use of the SPME technique coupled with GC-MS to determine multi-residue pesticides is found to be applicable in environmental, pharmaceutical, food, clinical, forensic samples in three modes (DI-SPME, HS-SPME and MD-SPME). This has gained much recognition due to its advantage over the classical or previous sample pretreatment methods such as SPE, LLE, LDME, HFME and DLME. Before applying SPME coupled to a GC-MS detector, several conditions need to be met in order to accomplish enhanced extraction rate, efficiency and sensitivity of experimental procedures. .. Read More»

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