Journal of Clinical Case Reports

Kapil Dev Negi

Publications

• Research Article
  Evaluation of Plasma D-Dimer Level as a Predictve Marker of Advanced Carcinoma Breast
  Author(s): Bhavesh Devkaran, Kapil Dev Negi, Sudershan Sharma and Jaswal SBhavesh Devkaran, Kapil Dev Negi, Sudershan Sharma and Jaswal S
  
  Purpose: Evaluation of plasma d-dimer level as a predictive marker of advanced carcinoma breast. Backround: The relationship between malignancy and thrombosis is known for over 100 years. Thrombocytosis, an increase in fibrinogen and fibrin degradation products like D-dimer, a rise in factors V,VII,VIII , IX, and XI levels, and a decrease in antithrombin III , are seen in cancer patients. Extracellular remodeling of fibrin is essential for angiogenesis in tumors, and activation of intravascular fibrin formation and degradation has been shown to occur in the plasma of breast cancer patients. Material and methods: This study was conducted in the Department of Surgery in I.G.M.C. Shimla & included 90 patients admitted in surgery ward/ presenting in the O.P.D. Patients were randomized i.. Read More»
  DOI: 10.4172/2165-7920.1000547

  Abstract PDF