Journal of Clinical Case Reports

Katharina Lisenko

Publications

• Case Report
  Giant Cell Arteritis Related to Granulocyte-Colony-Stimulating Factor Administration
  Author(s): Katharina Lisenko, Norbert Blank, Patrick Wuchter, Tim Weber, Martin Cremer, Mark Kriegsmann, Anthony D Ho and Mathias Witzens-HarigKatharina Lisenko, Norbert Blank, Patrick Wuchter, Tim Weber, Martin Cremer, Mark Kriegsmann, Anthony D Ho and Mathias Witzens-Harig
  
  Objective: Granulocyte-colony-stimulating factor (G-CSF) is routinely used to mobilize stem cells for peripheral blood stem cell (PBSC) collection by leukapheresis. Although generally considered safe and effective, G-CSF has been reported to cause severe side-effects in rare cases. Methods and Results: We report a case of a 65-year-old woman with diffuse large B-cell lymphoma, who received G-CSF for PBSC mobilization for ten days and developed fever of unknown origin. She was diagnosed with giant cell arteritis (GCA) related to G-CSF with aortic involvement based on typical findings obtained by contrastenhanced computed tomography and treated with high-dose prednisone. Conclusion: GCA might have to be considered as a rare but severe side effect of G-CSF administration. Imaging studies may help to identify large vessel vasculitis in cases that cannot b.. Read More»
  DOI: 10.4172/2165-7920.1000788

  Abstract PDF