Cancer Science & Therapy

Kathryn Jinmei Tian

Publications

• Mini Review
  High Rate of Glycolysis and Cancer
  Author(s): Kathryn Jinmei TianKathryn Jinmei Tian
  
  One hundred years ago, abnormal metabolism of cancer cell was regarded as one of the most important pathological features of malignancy. Recently, with the development of system biology, researchers regained the interest in regulating cancer metabolism. In 1920s’, Dr. Otto Warburg discovered that, even when oxygen is ample, malignant cells still prefer the anaerobic glycolysis, and the rate of glucose uptake is high while the overall glycolysis increases. Cancer cells divide faster than normal cells, hence they need more bioenergy, and they need to change their metabolism to produce the extra energy. In recent 20 years, the link between high rate of glycolysis and cancer was re-evaluated and has inspired enthusiasm upon research into the metabolism of cancer cells. Novel diagnostic methods and new drugs were created by the understanding of the features of cancer metabolism. Glycoly.. Read More»
  DOI: 10.4172/1948-5956.1000531

  Abstract PDF