Japan
Research Article
Evaluation of Endometrial Endometrioid Carcinoma Grade Using Ultraviolet-
Visible-Light Microscopic Spectroscopy
Author(s): Haruhiko Yoshioka, Hironori Kondo, Kayo Horie, Kiyotada Washiya and Jun WatanabeHaruhiko Yoshioka, Hironori Kondo, Kayo Horie, Kiyotada Washiya and Jun Watanabe
Objective: The objective of this study was to investigate the possibility of an objective index to evaluate the grades of endometrial endometrioid carcinomas by analyzing the spectral values of ultraviolet(UV) and visible(Vis) transmittances, and the degree of UV- absorbing materials influencing nuclear colors using ultraviolet- visible-light microscopic spectroscopy (UV-Vis MS).
Study design: The materials were histological preparations from 4 patients, each with proliferative-phase endometrium (PPE) and grade 1(G1) and grade 3 (G3) of endometrial endometrioid carcinomas. Both spectra were measured in the same 50 nuclei of each specimen.
Results: 1) In the ultraviolet spectrum, transmittance of 260, 280, 300, and 320 nm were decreased in G3 compared to those in G1. All of the ultraviolet absorbing materials increased .. Read More»
DOI:
10.4172/2157-7099.1000381
Journal of Cytology & Histology received 2334 citations as per Google Scholar report