Journal of Spine

Kazuhiko Sugiyama

Publications

• Case Report
  A Case of a Primary Radiation-Induced Malignant Peripheral Nerve Sheath Tumor in the Cauda Equina in a Patient with Neurofibromatosis Type 2
  Author(s): Takafumi Mitsuhara, Satoshi Yamaguchi, Masaaki Takeda, Kuniki Eguchi, Mizuki Morishige, Kazuhiko Sugiyama and Kaoru KurisuTakafumi Mitsuhara, Satoshi Yamaguchi, Masaaki Takeda, Kuniki Eguchi, Mizuki Morishige, Kazuhiko Sugiyama and Kaoru Kurisu
  
  Background: Radiation-induced malignant peripheral nerve sheath tumors (MPNSTs) may occur in any irradiated area of the body where primary malignant lesions existed. However, there have been isolated reports regarding the radiation-induced transformation of spinal schwannomas into MPNSTs in patients with neurofibromatosis type 2 (NF2). Case material: A 47-year-old woman presented with gradually progressive paraparesis, bowel-bladder dysfunction, and acute consciousness disturbance. Fifteen years previously, she had undergone radical hysterectomy with adjuvant intraoperative para-aortic radiotherapy for the treatment of uterine cervical cancer. Magnetic resonance (MR) images of the brain revealed hydrocephalus and multiple intracranial tumors in bilateral oculomotor and vestibular nerves. Spinal MR images revealed numerous tumors in the cervical.. Read More»
  DOI: 10.4172/2165-7939.1000129

  Abstract PDF