Japan
Short Communication
Close Association of Hypoadiponectinemia and Increased Insulin Resistance in Non-Obese Japanese Type 2 Diabetes with Visceral Adiposity
Author(s): Hodaka Yamada, Daisuke Suzuki, Masafumi Kakei, Ikuyo Kusaka, San-e Ishikawa and Kazuo HaraHodaka Yamada, Daisuke Suzuki, Masafumi Kakei, Ikuyo Kusaka, San-e Ishikawa and Kazuo Hara
Objective: Visceral fat accumulation because of obesity plays a central role in metabolic syndrome and causes cardiovascular disease (CVD).
Methods: The aims of this study were to investigate associations between visceral fat accumulation and adipokines in non-obese type 2 diabetic patients.
Results: In total, 138 type 2 diabetic patients were enrolled, with a mean age of 64 years. Among the participants, 69 were males. We found that serum high-molecular-weight adiponectin level was decreased, C-reactive protein increased, and using homeostatic model assessment of insulin resistance was also increased in non-obese patients with visceral adiposity (body mass index: BMI, <25 kg/m2; visceral fat area: VFA, ≥ 100 cm2) compared with those without visceral adiposity (BMI, <25 kg/m2, VFA, <100 cm2). VFA in non-alcoh.. Read More»
DOI:
10.4172/2167-0943.1000215
Journal of Metabolic Syndrome received 48 citations as per Google Scholar report