Japan
Research Article
Analysis of 19 preservatives in Polyvinyl Alcohol Cooling Towels Used in Japan by High Performance Liquid Chromatography with Photo Diode Array Detector
Author(s): Tsuyoshi Kawakami, Kazuo Isama and Yoshiaki IkarashiTsuyoshi Kawakami, Kazuo Isama and Yoshiaki Ikarashi
The cases of contact dermatitis due to using polyvinyl alcohol (PVA) towel containing isothiazolinone preservatives have been reported in Japan and we had investigated the concentrations of isothiazolinones and the removal of these preservatives from PVA towels by washing before initial use in the previous study conducted from 2011 to 2012. However, the clinical information regarding contact dermatitis due to using PVA cooling towels containing other preservatives was provided from the supplier of PVA towel in the summer of 2013. Thus, we analyzed 19 preservatives in 21 PVA towels by high performance liquid chromatography with photo diode array detector in this study. A good separation of these preservatives was observed using InertSustain® Phenyl column and 0.1 % formic acid solution as the mobile phase. 2-Methyl-4-isothiazolin-3-one and 5-chloro-2-methyl-4- isothiazolin-3-one we.. Read More»
DOI:
10.4172/2380-2391.1000122
Journal of Environmental Analytical Chemistry received 1781 citations as per Google Scholar report