Kenji Shimizu
Managing Director, Asia Pacific Operations at Palomar Medical Technologies, Inc.
Biography
Several different transforming genes have been observed in the DNA of a variety of tumours and tumour cell lines of human and rodent origin by the ability of these genes to induce morphological transformation in NIH 3T3 cells
1–5. The transforming gene found in a human bladder carcinoma cell line, T24, is H-
ras-1, the human homologue of the Harvey sarcoma virus oncogene (v-H-
ras)
6–9. In the present study we have compared the H-
ras-1 genes cloned from T24 and normal human DNA.