United Kingdom
Case Report
Florid Endocervical Microglandular Hyperplasia in Association with Tamoxifen
Treatment
Author(s): Ayakannu T, Hew WSR, Brown L, Ismail S, Maulik TG, Kiberu SW and Anthony H TaylorAyakannu T, Hew WSR, Brown L, Ismail S, Maulik TG, Kiberu SW and Anthony H Taylor
Background: Although tamoxifen has well documented oestrogen-like effects in the endometrium and ectocervical squamous epithelium, its effects on the endocervix are poorly documented.
Case report: We report a case of an 88 year-old woman who presented with postmenopausal bleeding after receiving tamoxifen for 16 months following a diagnosis of Grade 2 invasive and in situ carcinoma of breast. Endometrial biopsy was performed revealing either atypical hyperplasia or adenocarcinoma. She underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and lymph gland sampling. Histopathological examination of the uterus showed an endometrioid carcinoma (FIGO Grade 2) at the endometrium. In addition, there was extensive florid endocervical microglandular hyperplasia.
Conclusion: Endocervical microglandular hyperplas.. Read More»
DOI:
10.4172/2157-7099.1000375
Journal of Cytology & Histology received 2476 citations as per Google Scholar report