Journal of AIDS & Clinical Research

Kigozi D Ssebaggala

Publications

• Research Article
  A Comparative Assessment of the EIA/PCR HIV Test Results among Weakly Reactive Samples on Any of Determine HIV1/2, Statpak and Unigold Rapid Test Kits
  Author(s): Kigozi D Ssebaggala, Lutalo Tom, Maria J Wawer, Sserwadda David, Steven J Reynolds, Nalugoda Fred, Kigozi Godfrey, Ronald H Gray, Kalibbala Sarah and Muwanika RichardKigozi D Ssebaggala, Lutalo Tom, Maria J Wawer, Sserwadda David, Steven J Reynolds, Nalugoda Fred, Kigozi Godfrey, Ronald H Gray, Kalibbala Sarah and Muwanika Richard
  
  Objective: The Government of Uganda recommends the serial HIV rapid testing algorithm where weakly reactive results on any of the three: Determine, Statpak and Unigold are interpreted as positive. We assessed the proportion of weak positive (WP) rapid results against confirmed results. Methods: We generated cross tabulations using Stata 3.0 to compare the WP rapid test results on each kit in the algorithm against final results on EIA/PCR to assess the proportion of samples confirmed to be HIV negative on ELISA and/or qualitative DNA PCR. We also generated Positive Predictive Values (PPV) to find the proportion of results that were true positives. Results: A total of 231 weak positive (WP) results were selected. 71 were WP on Determine HIV1/2, 149 on Statpak and 11 on Unigold. We found that 35.2% of the WP results on Determine were confirmed Negative by EIA/PCR test with a Positive P.. Read More»
  DOI: 10.4172/2155-6113.1000670

  Abstract PDF