Taiwan
Research Article
Probiotic Potential of Lactobacillus Strains on the Adipogenesis of 3T3-L1 Cells
Author(s): Kang CH, So JS, Han SH, Kim YG, Jeong Y, Kim JS and Paek NSKang CH, So JS, Han SH, Kim YG, Jeong Y, Kim JS and Paek NS
Obesity is the most common health problem in developed countries and is considered a significant risk factor for many major human diseases. This study aimed to evaluate the inhibitory effect of lactic acid bacteria isolated from the human vagina on adipocyte differentiation in 3T3-L1 preadipocytes. We screened 26 strains of lactic acid bacteria to test their effects against obesity. Among the tested strains, Lactobacillus gasseri MG2855 exhibited a lipase inhibitory activity of 11.84% and inhibited relative lipid content of 3T3-L1 cells (96.21%) at a concentration of 1,000 μg/mL. The survival rate of L. gasseri MG2855 in 0.3% bile salt was 88.47%, and the survival rate after incubation for 3 h in pH 3.0 was 78.64%. L. gasseri MG2855 showed higher sensitivity to erythromycin, chloramphenicol, tetracyclin, and cephalothin in 16 antibiotic sensitivity tests. These.. Read More»
DOI:
10.4172/2572-4134.1000124
Journal of Food & Industrial Microbiology received 160 citations as per Google Scholar report