Tanzania
Research Article
Busulfan Dosing Literature Review
Author(s): Cynthia L Gong, Rezvani AR, Kim T and Studdert ALCynthia L Gong, Rezvani AR, Kim T and Studdert AL
Introduction: There is debate regarding the use of busulfan every 6 hours (q6 h) compared to every 24 hours (q24 h) in patients undergoing hematopoietic cell transplantation.
Objectives: To review the literature to determine whether there is a significant difference between dosing busulfan q6 h vs. q24 h in adults, and to review dosing strategies to optimize daily dosing.
Methods: A literature search was conducted in PubMed with the terms “busulfan” and “transplant” and “24” in all fields. Results were further refined by using the terms “busulfan” and “transplant” and “pharmacokinetics”. Titles were then reviewed for relevance, and the remaining articles reviewed by abstract. Articles deemed relevant were then read in more thorough detail, and refere.. Read More»
DOI:
10.4172/2165-7831.1000204
Journal of Blood & Lymph received 443 citations as per Google Scholar report