India
Research Article
Determination of Immune Potentials of Recombinant Fusion and Recombinant Haemagglutinin-Neuraminidase Antigens of Newcastle Disease Virus (NDV)
Author(s): Maheswarappa G, Vijayarani K, Kumanan K and Uttar Kumar AMaheswarappa G, Vijayarani K, Kumanan K and Uttar Kumar A
Chicken are the most abundant birds in the world with a population of more than 24 billion. They are mainly kept for egg and meat production. Important economic lossess for the industry can occur, due to viral diseases such as Avian influenza and Newcastle disease. Vaccination is the only available tool to curb the outbreak of epidemics in poultry. Till today only few good vaccines are available to prevent the epidemic diseases. Recombinant DNA technology led to the development of recombinant vaccines and subunit vaccines but immunopotency of recombinant vaccines and subunit vaccines are not well understood in Newcastle disease vaccines. Hence, in this study, we cloned and expressed the fusion and haemagglutinin-neuraminidase genes of NDV in insect cells. Immunological study was carried out to assess the immunopotency of rec-F and rec-HN antigens in commer.. Read More»
DOI:
10.4172/2157-7579.1000192
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