Journal of Cytology & Histology

Kung-Chao Chang

Publications

• Case Report
  Hepatic Epithelioid Hemangioendothelioma with Cecal Metastasis in a Natural Course: A Case Report
  Author(s): Ying-Ren Chen, Chien-Hsien Lai, Liang-Yi Hung and Kung-Chao ChangYing-Ren Chen, Chien-Hsien Lai, Liang-Yi Hung and Kung-Chao Chang
  
  Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor of low malignant potential that occurs mostly in soft tissue. So far, only two cases of EHE involving the intestine have been recorded. Here, we describe a rare case of cecal EHE due to a subsequent metastasis from the primary liver tumor three years after initial diagnosis. A 74- year-old man had sudden onset of epigastralgia for 24 hours. The abdominal CT revealed an ileocecal mass with a small bowel obstruction, and extensive tumor involvement in the liver was noted. He received an emergent right hemicolectomy for relief of the ileus. Unfortunately, he expired four days later due to septic shock. The pathologic diagnosis of EHE prompted a molecular study for a WWTR1-CAMTA1 fusion. The Sanger sequencing results showed the fusion involved exon 4 of WWTR1 with exon 8 of CAMTA1. There is no standard treatment for hepatic E.. Read More»
  DOI: 10.4172/2157-7099.1000398

  Abstract PDF