China
Case Report
Life-threatening Capillary Leak Syndrome in an Adult with Refractory Acute Myeloid Leukemia during Allogeneic Transplantation: a Case Report and Review of Literature
Author(s): Yi-Zhi J, Lai-Quan H, Gui-Ping S, Yan D, He-Sheng H and Dong-Ping HuangYi-Zhi J, Lai-Quan H, Gui-Ping S, Yan D, He-Sheng H and Dong-Ping Huang
Background: Although allogeneic hematopoietic stem cell transplantation (allo-HSCT) offers the possibility of cure for hematological malignancies, various complications have been described. Capillary leak syndrome (CLS) has been previously observed in HSCT patients. CLS is a rare disease characterized by recurrent episodes of generalized edema and severe hypotension along with hypoproteinemia.Case Report: A 27-year-old Chinese man, diagnosed with refractory acute myeloid leukemia, was treated with a haploidentical stem cell transplant combined with an unrelated umbilical cord blood unit. The patient developed fatal CLS during the 9th day of the conditioning therapy. Conclusion: Since it is difficult to distinguish between CLS and other early complications during allo-HSCT, our report highlights the need for rigorous investigation of identifying CLS an.. Read More»
DOI:
10.4172/2161-0991.1000S4-003
Transplantation Technologies & Research received 223 citations as per Google Scholar report