Journal of Computer Science & Systems Biology

Lakshmi Pillai

Publications

• Research Article
  Modeling Calcium Dependent Protein Kinase Isoform 1 from Cicer arietinum (chick pea)
  Author(s): Lakshmi Pillai and K. R. PardasaniLakshmi Pillai and K. R. Pardasani
  
  The homology based 3-Dimensional structure prediction of calcium dependent protein kinase Isoform 1 From Cicer arietinum (chick pea) was carried out using bioinformatics tools. The CPK1 sequence on Protein BLAST analysis for homology search revealed 100 hits and Out which a few had significant E score (E <0.005) and better sequence similarity. Multiple sequence alignment analysis of CPK1 using MultAlin and HHpred showed above 90% similarities with protein sequences of Thermotoga petriphila (Hypothetical protein), Geobacillus stereothermophilus (1w91; 99.5%; E score=1.2 E-11), Thermoanaerobacterium saccharolyticum (1uhv; 99.4%; E score=2.9 E-11) and Bacillus stereothermophilus (1qw9; 98.5%; E score=4.9 E-6) from the PDB database. The secondary structure of CPK1 using PSIPRED VIEW revealed many helices, strands and coils in the protein structure. The tert.. Read More»
  DOI: 10.4172/jcsb.1000084

  Abstract PDF