Pulmonary & Respiratory Medicine

Lara Kovell

Publications

• Research Article
  Predictors of Functional Capacity in Patients with Pulmonary Hypertension
  Author(s): Rui Plácido, Susana Martins, João Silva Marques, Lara Kovell, Susana Gonçalves, Ana G. Almeida, António Nunes Diogo and Fausto PintoRui Plácido, Susana Martins, João Silva Marques, Lara Kovell, Susana Gonçalves, Ana G. Almeida, António Nunes Diogo and Fausto Pinto
  
  Introduction: The 6-minute walk test (6 MWT) distance is frequently used in the prediction of pulmonary hypertension (PH) prognosis. However, potential surrogates of this measure have not been established. We aim to describe the clinical, echocardiographic, and laboratorial criteria determining the 6 MWT distance in patients with PH. Methods: In 22 consecutive PH patients, functional capacity was evaluated by the 6 MWT distance and compared with levels of neurohormonal activation biomarkers and echocardiographic parameters for right ventricular (RV) function. Results: A correlation between the 6 MWT distance and several clinical parameters was found: Borg’s pre-test classification (R=-0.46; p=0.038); WHO functional class (p=0.029). Patients with higher levels of aldosterone (R=-0.46; p=0.030), renin (R=-0.43;.. Read More»
  

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