China
Research Article
Prevention of Preeclampsia with Aspirin Therapy in the Second Trimester and Pregnancy Outcome: A Meta-analysis
Author(s): Wei YY, Pang LH, Liang HF, Chen HY, Fan XJ, Zhang LJ, Chen XF and Li PWei YY, Pang LH, Liang HF, Chen HY, Fan XJ, Zhang LJ, Chen XF and Li P
Background: Low-dose aspirin (LDA, range from 60-150 mg/d) therapy has been used to prevent preeclampsia (PE) for many years. However, whether LDA could positively affect pregnancy outcome remains unknown. Purpose: We performed this meta-analysis to assess the effectiveness of LDA therapy in women at high risk for PE.
Methods: We searched studies published from January 1985 to February 2015. All the studies were search from the databases of PubMed, EMBASE, Cochrane, ScienceDirect, and Biosis Preview. The association between PE and pregnancy outcome with aspirin therapy was assessed by odds ratios (ORs) and 95% confidence intervals (CIs).
Results: Thirteen articles involving 6735 participants were included in the final meta-analysis. When all studies were pooled into the meta-analysis, a statistically significant effect w.. Read More»
DOI:
10.4172/2157-7420.1000225
Journal of Health & Medical Informatics received 2128 citations as per Google Scholar report