Journal of Bioanalysis & Biomedicine

Li Qin Zhang

Publications

• Research Article
  Nicotinamide Phosphoribosyltransferase in Human Diseases
  Author(s): Li Qin Zhang, Daniel P. Heruth and Shui Qing YeLi Qin Zhang, Daniel P. Heruth and Shui Qing Ye
  
  Nicotinamide phosphoribosyltransferase (NAMPT) was first reported as a pre-B-cell colony enhancing factor in 1994 with little notice, but it has received increasing attention in recent years due to accumulating evidence indicating that NAMPT is a pleiotropic protein such as a growth factor, a cytokine, an enzyme and a visfatin. Now, NAMPT has been accepted as an official name of this protein. Because of NAMPT’s multiple functions in a variety of physiological processes, their dysregulations have been implicated in the pathogenesis of a number of human diseases or conditions such as acute lung injury, aging, atherosclerosis, cancer, diabetes, rheumatoid arthritis and sepsis. This review will cover the current understanding of NAMPT’s structure and functions with an emphasis on recent progress of nicotinamide phosphoribosyltransferase’s pathological roles in var.. Read More»
  DOI: 10.4172/1948-593X.1000038

  Abstract PDF