Molecular Biology: Open Access

Lin Wang

Publications

• Research Article
  Parathyroid Hormone-Like Hormone (PTHLH) Feedback Mitosis to Downstream DNA Replication Coupling Postreplication Repair-Induced Cell Proliferation Network in No-Tumor Hepatitis/Cirrhotic Tissues (HBV or HCV Infection) by Systems-Theoretical Analysis
  Author(s): Juxiang Huang, Lin Wang, Minghu Jiang, Hong Lin, Lianxiu Qi and Haizhen DiaoJuxiang Huang, Lin Wang, Minghu Jiang, Hong Lin, Lianxiu Qi and Haizhen Diao
  
  Based on analysis of biological processes in the same low expression Parathyroid Hormone-Like Hormone (PTHLH) activated feedback mitosis and downstream DNA replication-mediated cell proliferation Gene Ontology (GO) network of no-tumor Hepatitis/Cirrhotic Tissues (HBV or HCV infection) compared with the corresponding high expression (fold change ≥2) activated (Gene Ontology) GO network of human Hepatocellular Carcinoma (HCC), we proposed PTHLH activated network that upstream consisted of cell division, cell proliferation, mitosis, mitotic checkpoint, nucleosome assembly, spindle organization and biogenesis; Downstream network cell cycle, cell cycle arrest, centrosome cycle, chromosome segregation, DNA replication, DNA replication checkpoint, G1/S transition of mitotic cell cycle, mitotic chromosome condensation, mitotic G2 checkpoint, mitotic spindle checkpoint,.. Read More»
  DOI: 10.4172/2168-9547.1000106

  Abstract PDF