Environmental & Analytical Toxicology

Lucia Rocco

Publications

• Research Article
  Genotoxicity in Zebrafish (Danio rerio) Exposed to two Pharmacological Products from an Impacted Italian River
  Author(s): Lucia Rocco, Angelina Izzo, Giovanna Zito, Carmela Peluso and Vincenzo StingoLucia Rocco, Angelina Izzo, Giovanna Zito, Carmela Peluso and Vincenzo Stingo
  
  The aim of this study was to identify the pharmaceutical substances in the waters of the river Volturno in Campania and to identify the genetic alterations that they induce in fish. These vertebrates, living in water, are particularly sensitive to polluting substances dissolved in their water that interact with DNA leading to the formation of additions or breaks, as well as to the loss or chemical modifications of the bases, because they can conserve and concentrate the substances discharged into their natural habitat. A preventive chemical analysis was carried out on the waters of the river Volturno. The results showed the presence of various drugs, among which Carbamazepine, a known antiepileptic and Diclofenac, a non-steroid anti-inflammatory agent. The genotoxicity of these two compounds was evaluated in 155 individuals of Danio rerio using the Comet Test, the Diffusion Assay and .. Read More»
  DOI: 10.4172/2161-0525.1000103

  Abstract PDF