Molecular Biomarkers & Diagnosis

Lucien Marchand

Publications

• Research Article
  Diagnostic Value of Cell-free Circulating Micrornas for Obesity and Type 2 Diabetes: A Meta-analysis
  Author(s): Audrey Villard, Lucien Marchand, Charles Thivolet and Sophie RomeAudrey Villard, Lucien Marchand, Charles Thivolet and Sophie Rome
  
  Type 2diabetes mellitus (T2DM) is the most common metabolic disorder worldwide. Because of population aging and increasing trends toward obesity and sedentary lifestyles, the number of affected individuals is increasing at worrisome rates. While both environmental and genetic factors are known to contribute to the development of T2DM, continuous research is needed to identify specific biomarkers that could aid both in prevention of the disease and development of newer therapeutic options. Circulating miRNAs are considered as potential biomarkers because they are stable and resistant to degradation by blood RNAses and are modified under different pathophysiological conditions. In this study we carried out a systematic electronic search on PubMed to retrieve all articles that have investigated circulating miRNAs for diagnosing obesity andT2DM in human. We also included lifestyle interve.. Read More»
  DOI: 10.4172/2155-9929.1000251

  Abstract PDF