Iraq
Research Article
Effects of Kurdistan Honey on the Tongue of Chemotherapy Treated Albino Rats Immunohistochemical Study)
Author(s): Ali Sultan Al-Refai, Lukman Fawzi and Ameera Kamal KhalilAli Sultan Al-Refai, Lukman Fawzi and Ameera Kamal Khalil
Background and Objectives: Mucositis can be a dose-limiting toxicity of cancer chemotherapy with direct effects on patient survival; therefore an effective intervention is considered a high priority in cancer patient. The aim of the present study was to evaluate the effectiveness of honey as a preventive treatment for the methotrexate (MTX) induced oral mucositis.
Materials and Methods: In current study forty females Albino rats, weighing 250-300 g were used in the study. For the induction of oral mucositis, 60 mg/kg of MTX was administered intraperitoneally to each animal in the study group at day 4. The control animals were intraperitoneally injected by normal saline in the same manner and dose like MTX. At the beginning of the experiment, the rats in each group were randomly divided into two groups: Distilled water treated group and honey t.. Read More»
DOI:
10.4172/2157-7099.1000272
Journal of Cytology & Histology received 2476 citations as per Google Scholar report