Journal of AIDS & Clinical Research

Maciej Krol

Publications

• Short Communication
  Increased Exhaled Hydrogen Peroxide in Human Immunodeficiency Virus- Infected Patients without Clinical Signs and Symptoms of Opportunistic Lung Disease
  Author(s): Maciej Krol, Arkadiusz Balcerowski, Maria Luczynska, Urszula Szkudlarek and Dariusz NowakMaciej Krol, Arkadiusz Balcerowski, Maria Luczynska, Urszula Szkudlarek and Dariusz Nowak
  
  Background: HIV-infected subjects present with decreased antioxidant defense and increased activation of inflammatory cells which may lead to overproduction of oxidants. This study determined whether HIV-infected patients without clinical signs and symptoms of opportunistic lung disease (OLD-negative) exhaled more H2O2 than healthy controls and whether there was association between the exhalation of H2O2 and whole blood chemiluminescence (CL) and clinical variables. Methods: A cross-sectional study was conducted. H2O2 in exhaled breath condensate and CL, resting and agonist-induced with N-formyl-methionyl-leucyl-phenylalanine (fMLP) were measured in 36 OLD-negative patients and 14 healthy controls. Univariate linear regression was used to summarize the average relationship and quantile regression analyzed the relationship at different points of the exhaled H2O2 distribution. Multivari.. Read More»
  DOI: 10.4172/2155-6113.1000183

  Abstract PDF