Nuclear Medicine & Radiation Therapy

Madhava R. Kanakamedala

Publications

• Research Article
  3D Image based Customized versus Standard Treatment Planning for Cervical Cancer High Dose Rate Brachytherapy with Tandem and Ovoids
  Author(s): Paul Mobit, Michael C. Baird, Madhava R. Kanakamedala, Waleed F. Mourad, Satyaseelan Packianathan, Srinivasan Vijayakumar and Claus Chunli YangPaul Mobit, Michael C. Baird, Madhava R. Kanakamedala, Waleed F. Mourad, Satyaseelan Packianathan, Srinivasan Vijayakumar and Claus Chunli Yang
  
  Purpose and Objective(s): To investigate the advantages of volumetric treatment planning in HDR brachytherapy for cervical carcinoma compared to standardized loading based on 2-D planning techniques. Materials and Methods: Our institution uses volume-based 3-D planning for each tandem and ovoid (T&O) insertion for HDR brachytherapy in the treatment of advanced cervical carcinoma. Here, we attempt to define the benefits of this approach. We re-planned 48 CT-based treatment plans on 12 patients (treated in our facility between February, 2009 and February, 2010) using a commonly used 2-D standard HDR loading of the T&O. All patients had received 4 fractions of 6.5 Gy or 5 fractions of 5.5 Gy to point H or A. The following organs at risk (OARs) were contoured: rectum, bladder, sigmoid, and small bowel. Our customized planning approach required the adjustment of source dwel.. Read More»
  DOI: 10.4172/2155-9619.1000239

  Abstract PDF