India
Research Article
2D-QSAR Studies of Substituted Pyrazolone Derivatives as Anti-Inflammatory Agents
Author(s): Rishikesh V. Antre, Rajesh J. Oswal, Sandip S. Kshirsagar, Pranita P. Kore and Madhavi M. MuthaRishikesh V. Antre, Rajesh J. Oswal, Sandip S. Kshirsagar, Pranita P. Kore and Madhavi M. Mutha
A QSAR study was performed on a series of substituted pyrazolone derivatives. The compounds in the selected series were characterized by spatial, molecular and electrotopological descriptors using QSAR module of molecular design suite (V-Life MDS 4.0). In present research paper we reported 2D-QSAR studies of substituted pyrazolone derivatives. Correlations between inhibitory activities and calculated predictor variables were established through partial least square regression (stepwise forward) method.f
.. Read More»
DOI:
10.4172/2161-0444.1000127
Medicinal Chemistry received 6627 citations as per Google Scholar report