Egypt
Research Article
The Utility of Automated HCV Core Antigen Assay as an Alternative to PCR in Chronic HCV Egyptian Patients
Author(s): Ehab M Abd El-reheem, Magdy Fouad, Hanaa Kh Fath El-bab and Waleed M Abd El-HmeedEhab M Abd El-reheem, Magdy Fouad, Hanaa Kh Fath El-bab and Waleed M Abd El-Hmeed
Hepatitis C is a disease with a significant global impact. Although the detection and quantitation of HCV RNA have been the standard method for the diagnosis and assessing individual patient response to the antiviral drug regimen, it is very sensitive testing, expensive, labor intensive, and requires technical skill.
Since the HCV core Ag assay is easy to perform in an immunoassay format, cheap, and less prone to sample carryover contamination compared to nucleic acid tests, There is an increasing interest to use HCV core antigen as a reflex test for seropositive individual to identify the active HCV infection also can be used to detect the early HCV infection.
Aim of the work: To compare the diagnostic accuracy of HCV core antigen with HCV-PCR in chronic HCV Egyptia.. Read More»
DOI:
10.4172/2155-9929.1000275
Molecular Biomarkers & Diagnosis received 2054 citations as per Google Scholar report