Veterinary Science & Technology

Mahanama De Zoysa

Publications

• Research Article
  Chitosan Silver Nano Composites (Cagncs) as Potential Antibacterial Agent to Control Vibrio tapetis
  Author(s): Dananjaya SHS, Godahewa GI, Jayasooriya RGPT, Chulhong OH, Jehee Lee and Mahanama De ZoysaDananjaya SHS, Godahewa GI, Jayasooriya RGPT, Chulhong OH, Jehee Lee and Mahanama De Zoysa
  
  Nanocomposites exhibit high performance on antimicrobial activities and have the potential to be developed alternative antibiotics. In this study, antibacterial effects of chitosan silver nano composites (CAgNCs) were investigated using pathogenic Vibrio tapetis as a bacterial model. Agar disc diffusion and turbidimetric assay results showed that CAgNCs could inhibit the growth of V. tapetis in concentration depended manner. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of CAgNCs against V. tapetis were 50 μg/mL and 100 μg/mL, respectively. The field emission scanning electron microscopy (FE-SEM) images analysis of V. tapetis showed severe structural damage to cells after treating CAgNCs at 75 μg/mL compared to un-treated bacteria. Moreover, CAgNCs induce the intracellular ROS level, leakage of nucle.. Read More»
  DOI: 10.4172/2157-7579.1000209

  Abstract PDF