Journal of Blood & Lymph

Mahran AM

Publications

• Case Report
  Ewing's Sarcoma as Second Malignancy after Bilateral Retinoblastoma: A Case Report and Literature Review
  Author(s): Sohier Yahia, Mansour AK, ALWakeel AA, Ahmad Darwish and Mahran AMSohier Yahia, Mansour AK, ALWakeel AA, Ahmad Darwish and Mahran AM
  
  Background: Children diagnosed with the hereditary form of retinoblastoma (Rb) have excellent survival, but face an increased risk of bone and soft tissue sarcomas. This predisposition to sarcomas has been attributed to genetic susceptibility due to inactivation of the RB1 gene as well as past radiotherapy for Rb. Objectives: To report the case of a child with hereditary form of bilateral RB, who developed Ewing’s sarcoma of the right femur 10 years after the Enucleation of the both eyes. Methods: The child was diagnosed as a case of bilateral RB at the age of 3 months. He was fully investigated and found to have locally advanced RB. Enucleation was done. The patient received chemotherapy and radiotherapy. At 14 years, he was investigated for a small swelling in his right lower leg. After extensive in.. Read More»
  DOI: 10.4172/2165-7831.1000113

  Abstract PDF