India
Research Article
Effect of �Ž�²Tricalcium Phosphate Nanoparticles Additions on the Properties of Gelatin-Chitosan Scaffolds
Author(s): Maji K and Dasgupta SMaji K and Dasgupta S
Bone tissue engineering, using a synthetic porous scaffold material provides some distinct advantages over autografting and allografting, and it is a rapidly growing alternative approach to heal damaged bone tissue. The current study focuses on fabrication and characterization of nano β-TCP incorporated gelatin- chitosan based composite scaffold for bone regeneration at the sites of musculoskeletal defects and disorders. Gelatin-chitosan scaffold reinforced with beta-tricalcium phosphate (β-TCP) nanopowder was fabricated through freeze drying of material’s suspension. From powder X-ray diffraction and Fourier transform infrared spectrometer analysis the presence of phase pure β-TCP powders in gelatin-chitosan matrix was confirmed. Gelatin-Chitosan-β- TCP (GCT) scaffold exhibited a homogenouos porous structure with an average pore size of 118 ± 11 μm.. Read More»
DOI:
10.4172/2090-5025.1000103
Bioceramics Development and Applications received 1050 citations as per Google Scholar report