Journal of Cytology & Histology

Makonnen E

Publications

• Research Article
  Toxicological Evaluations of the Crude Extracts and Fractions of Moringa stenopetala Leaves in Liver and Kidney of Rats
  Author(s): Bekesho Geleta, Makonnen E and Debella ABekesho Geleta, Makonnen E and Debella A
  
  Background: Moringa stenopetala is a medicinal plant that has been used in Ethiopian tradi-tional medicine as a remedy for treatment of hypertension, diabetes, malaria and stomach pain. Objective: The aim of this study was to assess the safety of the extracts and fractions of Moringa stenopetala leaves in liver and kidney of female Wistar rats. Methods: For acute toxicity study, the female Wistar rats were randomly divided into control and treatment groups that received distilled water and oral administration of single dose of 5000 mg/kg (n=5) extract, respectively and followed for 14 days. For repeated daily administration of extract, the female Wistar rats were Female Wistar rats were randomly divided into control and treatment groups (n=6). Treatment groups were given daily extracts (250, 500, and 1000 mg/kg) orally. Whereas, normal control received distilled water ad libitum for 1.. Read More»
  DOI: 10.4172/2157-7099.1000383

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