Egypt
Case Report
Histological and Histomorphometric Study of the Effect of Strontium
Ranelate on the Healing of One-Wall Intrabony Periodontal Defects in
Dogs
Author(s): Enas Ahmed Elgendy and Malak Yousef Mohamed ShoukhebaEnas Ahmed Elgendy and Malak Yousef Mohamed Shoukheba
Background: Periodontal regeneration aims at the restitution of supporting periodontal tissues lost due to periodontal diseases. With an aim of improving bone regeneration, strontium ranelate and related compounds were developed and have become increasingly popular in osteoporosis treatment. The aim of the present study was to evaluate the effect of the strontium ranelate 2% gel on the regeneration of the surgically created intrabony defect in dogs. Methods: One-wall intrabony defects (4 × 6 mm) were surgically created in the mesial aspect of second premolars bilaterally (split mouth study) in 10 dogs. Each intrabony defect underwent one of 2 treatment modalities: placebo gel (methyl cellulose gel)/collagen sponge (control site, group I) or strontium ranelate gel/collagen sponge (experimental site, group II). The animals were sacrificed with an overdose of anesthesia at 3 months.. Read More»
DOI:
10.4172/2157-7099.1000161
Journal of Cytology & Histology received 2334 citations as per Google Scholar report