Journal of AIDS & Clinical Research

Mame Thierno Dieng

Publications

• Case Report
  Stevens Johnson Syndrome and Toxic Epidermal Necrolysis Induced by Nevirapine among HIV-Infected Pregnant Women: Five Cases
  Author(s): Boubacar Ahy Diatta, Omar Gassama, Saer Diadie, Moussa Diallo, Suzanne Oumou Niang, Maodo Ndiaye, Assane Diop, Fatimata Ly and Mame Thierno DiengBoubacar Ahy Diatta, Omar Gassama, Saer Diadie, Moussa Diallo, Suzanne Oumou Niang, Maodo Ndiaye, Assane Diop, Fatimata Ly and Mame Thierno Dieng
  
  Introduction: The nevirapine is the most widely accused drug in toxidermias in patients living with HIV. It is responsible for toxic epidermal necrolysis called Lyell syndrome or Stevens Johnson syndrome, severe during pregnancy. We report five cases in pregnant women who are HIV-positive. Case reports: Five pregnant women aged 35 years on average with a mean gestational age of 29.6 weeks of amenorrhea were HIV1-positive.The mean CD4 count was 416/mm3. They had severe toxidermia such as Lyell syndrome or Stevens Johnson syndrome. These toxidermias appeared on average 26 days after taking antiretroviral triple therapy including nevirapine as part of the prevention of mother-to-child transmission of HIV (PMTCT). The outcome was favorable after discontinuation of antiretrovirals. Nevirapine was substituted with lopinavir/ritonavir. Newborns had received antiretroviral prophylaxis and we.. Read More»
  DOI: 10.4172/2155-6113.1000724

  Abstract PDF