Medicinal Chemistry

Mamoun Elsayed Shalaby

Publications

• Research Article
  Serum Prolactin and ImmunoglobulinE Levels in Psoriasis Vulgaris before and after NB-UVB Therapy
  Author(s): Mamoun Elsayed Shalaby, Hassan M Hassan, Mohammed I Aref and Asmaa D EbeidMamoun Elsayed Shalaby, Hassan M Hassan, Mohammed I Aref and Asmaa D Ebeid
  
  Babkground: Psoriasisis a chronic, inflammatory, T-cell mediated autoimmune disease. Many data demonstrating a significantly increased serum levels of both prolactin and IgE in patients with psoriasis vulgaris and reporting an association between their level and psoriasis severity. Existence of prolactin receptors on epidermal keratinocytes provides more support for the hypothesis that prolactin might have a role in the etiogenesis of psoriasis. Objectives of the study: It was aimed to estimate serum prolactin and immunoglobulin E levels in psoriasis vulgaris before and after NB-UVB therapy. Patients and methods: Fifty patients were submitted in this study. Severity of psoriasis was calculated using PASI score. Results: The results showed the following; a statistically significant difference between patients before an.. Read More»
  DOI: 10.4172/2161-0444.1000296

  Abstract PDF