Molecular Biomarkers & Diagnosis

Manash Saha

Publications

• Research Article
  Correlation of Serum Ferritin with Hepatic Iron Overload among Nontransfusion Dependent Beta Thalassaemia with Haemoglobin E Disease Patients from Eastern India
  Author(s): Prosanto Chowdhury, Manash Saha and Dhritidipa ChowdhuryProsanto Chowdhury, Manash Saha and Dhritidipa Chowdhury
  
   Introduction: Iron over load estimation was attempted by MRI R2* and serum ferritin, in non -transfusion dependent HbE Beta Thalassaemia patients. Methods: Seventy three patients selected on definite criteria were scanned and tested. Average age of the patients was 20.8 ± 11.14 years, 33 females and 40 male. Average hepatic iron concentration was determined to be 11.09 ± 11.74 mg/g of dry liver tissue and average serum ferritin was 972.44 ± 1121.51 ng/ml. Results: 81% of the patients had hepatic iron concentration more than 2 mg/g of dry liver tissue, whereas only 41% had serum ferritin level >500 ng/ml, irrespective of age. The hepatic iron overload pattern was heterogenous, where age and sex were not well determined variable predictors of such iron overload. Though, hi.. Read More»
  DOI: 10.4172/2155-9929.1000231

  Abstract PDF