Nuclear Medicine & Radiation Therapy

Manoj Gupta

Publications

• Case Report
  Exceptional Therapeutic Outcome of Metastatic Neuroendocrine Tumor with Peptide Receptor Radionuclide Therapy with Brief Review of Literature
  Author(s): Manoj Gupta, Partha S Choudhury, Shivendra Singh and Anurag MehtaManoj Gupta, Partha S Choudhury, Shivendra Singh and Anurag Mehta
  
  NETs are rare, heterogeneous group of neoplasm presented as chronic oncologic disease. Somatostatin analogue is the standard first line systemic therapy for mainly hormone control. No standard second line systemic treatment is available except everolimus which has no reported complete response. PRRT is an innovative molecular targeted treatment based on theragnostic concept for well differentiated NETs. We presented here a 63-year-old lady with grade 1 NET of rectum with lymphnodal and liver metastasis. She underwent sigmoid colostomy for bowel symptoms and started on sandostatin LAR. After progression, patient was treated with 4 cycles of 7.4GBq of 177Lu-DOTATATE at 10 weeks interval. No hematological and renal toxicity were noticed. Patient showed complete response in liver lesions & lymphnode.. Read More»
  DOI: 10.4172/2155-9619.1000333

  Abstract PDF