Brazil
Research Article
Do COPD and Healthy Subjects have Similar Acute Inflammatory Response Induced by Sub-maximum Effort Test?
Author(s): Krislainy De Sousa Corrêa, Adeliane Castro Da Costa, Ana Paula Perillo Ferreira Carvalho, José Laerte Rodrigues Da Silva Júnior, Maria Rosedália De Moraes, Ana Paula Junqueira-Kipnis and Marcelo Fouad RabahiKrislainy De Sousa Corrêa, Adeliane Castro Da Costa, Ana Paula Perillo Ferreira Carvalho, José Laerte Rodrigues Da Silva Júnior, Maria Rosedália De Moraes, Ana Paula Junqueira-Kipnis and Marcelo Fouad Rabahi
Introduction: COPD (chronic obstructive pulmonary disease) presents a low degree of systemic inflammation responsible for the disease’s extra pulmonary consequences. Its inflammatory profile can be altered by acute exercise. However, acute effects of a sub maximum test, capable of reproducing activities of daily living (ADL) in sedentary COPD individuals, are not well-known
Objective: To evaluate if the six-minute walk test (6MWT) is capable of altering interleukin-6 (IL-6) blood levels, tumoral necrosis factor alfa (TNF-α) and hypersensitive C reactive protein (hs-CRP) in relation to the basal level of COPD individuals.
Methods: 21 individuals with moderate and severe COPD and 8 healthy individuals, with no history of smoking, sedentary, matched by age were assessed regarding plasma levels of IL-6, TNF.. Read More»
DOI:
10.4172/2573-0312.1000123
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