Transplantation Technologies & Research

Mariano Ferraresso

Publications

• Editorial
  Hypothermic Machine Perfusion in Kidney Transplantation: Back to the Future?
  Author(s): Mariano Ferraresso and Evaldo FaviMariano Ferraresso and Evaldo Favi
  
  Static cold storage is currently the most used method of organ preservation worldwide. However, cutting edge technology and dramatic changes in the donor pattern have lately renewed the interest toward hypothermic machine perfusion. Marginal and cardiac death donors show higher rates of primary non function and delayed graft function compared to standard criteria donors. In this setting, machine perfusion may offer several theoretical advantages such as improved organ preservation, continuous graft evaluation, and ex-vivo conditioning of the graft before implantation. These topics have been recently reassessed by several studies. In particular, perfusion characteristics (renal resistance) and perfusate biomarker concentrations (lactate dehydrogenase, aspartate aminotransferase, heart-type fatty acid binding protein, and IL-18) during machine preservation, proved to be reliable tools t.. Read More»
  DOI: 10.4172/2161-0991.1000e135

  Abstract PDF