Molecular Biology: Open Access

Marum Meraj

Publications

• Research Article
  Evaluation of HFE Gene (C282Y) Mutation and Its Association Relation with Coronary Artery Diseases in Indian Population
  Author(s): Naseer Ue Din Shah, Abrar Ahmed, Falak Mushatq, Mohd Maqbool Reshi, Jasbir Kour, Hilal Ganaie and Marum MerajNaseer Ue Din Shah, Abrar Ahmed, Falak Mushatq, Mohd Maqbool Reshi, Jasbir Kour, Hilal Ganaie and Marum Meraj
  
  Background: The gene associated with the CAD disease was found out to be the HFE (High Iron Fe) gene and the disease is described with the two, missense mutations of the gene– C282Y and H63D. The focus of this study was to assess the C282Y mutation in CAD patients that results from transition of guanine to adenine (G-A) at the nucleotide position 845, which in turn changes cysteine to tyrosine at the 282nd position. Material and methods: C282Y mutation was analyzed by allele specific PCR (AS-PCR) in 100 samples which includes 96 males and 4 females. Data was collected from each patient. The blood from each patient was collected and analyzed for their cholesterol level, diabetes, RBS (Random blood sugar), LDL (low-density lipoprotein), HDL (high-density lipoproteins), TGL (Triglycerides), smo.. Read More»
  DOI: 10.4172/2168-9547.1000189

  Abstract PDF