Journal of Tissue Science and Engineering

Masahiko Minakami

Publications

• Mini Review
  Immunopathology of Apical Periodontitis and Refractory Cases
  Author(s): Etsuko Matsuzaki, Hisashi Anan, Noriyoshi Matsumoto, Junko Hatakeyama, Masahiko Minakami and Toshio IzumiEtsuko Matsuzaki, Hisashi Anan, Noriyoshi Matsumoto, Junko Hatakeyama, Masahiko Minakami and Toshio Izumi
  
  Apical periodontitis is a relatively frequently encountered disease in clinical dentistry; however, its pathogenesis and etiology are not easily elucidated. Therefore, it is not always cured, even when carefully following the highest standards of treatment and intractable apical periodontitis may occur. In addition, in long-term root canal treatment of difficult cases with intractable pain, there may be misunderstandings between the dentist and patient. While acute pain is an indispensable symptom in detecting lesions and disease, sustained chronic pain can decrease an individual’s quality of life with various negative outcomes, including decreased motivation to work. Therefore, endodontic treatments and pain control measures for a diseased tooth in intractable apical periodontitis must be developed. This review outlines the progression from the onset of the lesion and examines .. Read More»
  DOI: 10.4172/2157-7552.1000184

  Abstract PDF