Journal of Bioanalysis & Biomedicine

Masaya Kubota

Publications

• Review Article
  Dietary Phytochemicals as Cancer Preventive Agents: Efficacy and Mechanisms
  Author(s): Yohei Shirakami, Hiroyasu Sakai, Masaya Kubota, Takahiro Kochi and Masahito ShimizuYohei Shirakami, Hiroyasu Sakai, Masaya Kubota, Takahiro Kochi and Masahito Shimizu
  
  Despite significant advances in cancer therapeutic modalities, available anti-tumor drugs display limited efficacy and sometimes carry a risk of severe adverse side effect. Therefore, it is important to identify and develop cancer chemopreventive agents without toxicity. Epidemiological examinations in human populations and experimental rodent studies provide evidence that certain types of phytochemicals suppress development and growth of cancers at various organ sites. A number of clinical investigations have been also conducted and shown that dietary phytochemicals are able to inhibit tumorigenesis, indicating several phytochemicals are regarded as cancer chemopreventive agents. Epigallocatechin-3-gallate (EGCG), the major catechin in green tea, is considered as the most biologically active constituent in drinking tea with respect to inhibiting cell prol.. Read More»
  DOI: 10.4172/1948-593X.1000122

  Abstract PDF