French Guiana
Short Communication
Disseminated Histoplasmosis Seasonal Incidence Variations: A Supplementary Argument for Recent Infection?
Author(s): Matthieu Hanf, Antoine Adenis, Bernard Carme, Pierre Couppie and Mathieu NacherMatthieu Hanf, Antoine Adenis, Bernard Carme, Pierre Couppie and Mathieu Nacher
Background: In French Guiana, a recent study has shown that a major part of the histoplasmosis incidence temporal fluctuations could be explained by climatic factors and thus postulated that disseminated histoplasmosis cases could be in a large proportion due to new infections. The description of the seasonal pattern of histoplasmosis could potentially help to test this new hypothesis. Patients and methods: A study using prospective data from the French Hospital Database for HIV was conducted in order to determine seasonal variations of the incidence of first cases of disseminated histoplasmosis in HIV persons in Cayenne, French Guiana. Single failure Cox proportional hazards models were used. Results: After adjusting for CD4 counts and antiretroviral treatment, the incidence of disseminated histoplasmosis was significantly higher during the Short Wet Season–Long Dry Season than.. Read More»
DOI:
10.4172/2155-6113.1000175
Journal of AIDS & Clinical Research received 5061 citations as per Google Scholar report